Effect of the Menstrual Cycle and Hormonal Contraceptives on Human Papillomavirus Detection in Young, Unscreened Women

American College of Obstetrics and Gynecology
July 2010

Channa E. Schmeink, MD, Leon F. Massuger, MD, PhD, Charlotte H. Lenselink, MD, PhD, Wim G. Quint, PhD, Willem J. Melchers, PhD, and Ruud L. Bekkers, MD, PhD

OBJECTIVE: To estimate the effect of the menstrual cycle
and oral contraceptive pill (OCP) use on the prevalence,
incidence, and persistence of human papillomavirus

CONCLUSION: High-risk HPV detection was significantlyinfluenced by sample timing in the menstrual cycle(HPV).when analyzed separately for OCP users and women
with a natural menstrual cycle. This may have implications
in the future, when high-risk HPV detection may
become a primary screening tool in cervical cancer
(Obstet Gynecol 2010;116:67–75)

Read Full Article…

Comment from Leslie
I am posting this study for obvious – “natural cycle” reasons – however, I presented research and data to the FDA in March of this year on the need for menstrual cycle evaluation with the HPV vaccines.  The concerns regarding the dangers of this vaccine that my colleague Cynthia Janak and I presented are backed up by this study.


About Leslie Carol Botha

Leslie Carol Botha, WHE • Graduate from the National Institute of Whole Health • Co-author of Understanding Your Mind, Mood and Hormone Cycle • Internationally Recognized Expert on Hormones and Behaviors • Member of the Society for Menstrual Cycle Research • Program Director for Early Intervention and Prevention for At-Risk Adolescents - Gia Allemand Foundation for PMDD
This entry was posted in biology-Endocrine, Cycles-General and tagged , , , . Bookmark the permalink.

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